I’m a designer who is totally self-taught HTML and CSS. Some people criticize frameworks for being some kind of cheat that keeps you from learning CSS. But in fact, I feel like it’s the exact opposite. I’ve learned just as much from the Blueprint framework and the work it’s based on than any book or website tutorial. And most importantly, it gives me some best practices to follow that work every time. It takes much of the frustration and pain out of cross-browser coding.